Dynamics of left ventricular ejection fraction changes after surgical correction of mitral regurgitation

  • Received 04.01.2026
  • Revised 17.04.2026
  • Accepted 26.05.2026
  • Published 29.05.2026
  • 67 Views
  • Retrieved from Vol. 12, No. 1, 2026
  • Pages 55-62

 Mitral regurgitation is among the most prevalent disorders of the cardiac valvular apparatus and leads to chronic volume overload, left ventricular dilatation, and adverse ventricular remodelling. Despite the proven efficacy of contemporary surgical techniques for correcting mitral regurgitation, early recovery of left ventricular systolic function and the tempo of reverse remodelling remain clinically important. The aim of this study was to assess early postoperative changes in left ventricular systolic function and to analyse the dynamics of ejection fraction as a marker of the effectiveness of surgical correction of mitral regurgitation. The study enrolled 40 patients with grade III-IV mitral regurgitation who underwent either mitral valve repair (45%) or mitral valve replacement (55%). Transthoracic echocardiography was performed three times – preoperatively and at 1 and 3 months after surgery. Ejection fraction was calculated using the biplane Simpson method in accordance with ASE/EACVI recommendations. Statistical analysis was performed using built-in Microsoft Excel tools with computation of means, standard deviations, and percentage changes. Preoperatively, mean ejection fraction was 48.2%. At 1 month, it increased to 51.7%, and at 3 months to 54.9%, consistent with early reverse remodelling. The most pronounced improvement was observed in patients with a baseline ejection fraction <50% (increase of 8-10%). Mitral valve repair was associated with more favourable early dynamics than replacement (7-9% vs 5-6%). Overall, 75% of patients demonstrated a positive trajectory as early as one month postoperatively. Surgical correction of mitral regurgitation is associated with a substantial early improvement in left ventricular systolic function. Ejection fraction dynamics within the first 1-3 postoperative months represent an important prognostic tool, enabling assessment of procedural efficacy, the rate of reverse remodelling, and optimisation of subsequent patient management

reverse remodelling; echocardiography; systolic function; annuloplasty; valve replacement; postoperative recovery; myocardial contractility

https://doi.org/10.63341/ijmmr/1.2026.55
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